Projects
Antibodies for resistant Staphylococcus aureus
The main goal of this project is to develop human antibodies against multidrug resistant Staphylococcus aureus bacteria. Staphylococcus aureus is an opportunistic, but dangerous, community and hospital-acquired pathogen that employs a great variety of cell wall-associated and secreted virulence factors to subvert its human host. This gram-positive bacterium represents an increasing human health threat, especially for frail individuals, because of its amazing capacity to develop resistance to antibiotics. The objective of this proposal is to develop protective human antibodies for antimicrobial therapy against multidrug resistant and highly virulent S. aureus strains, including MRSA, with the ultimate aim of providing new strategies to combat life-threatening staphylococcal infections.
Partners: Biomade Technology, Erasmus MC (University Medical Center Rotterdam), IQ Corporation, Pepscan Presto BV, University Medical Center Groningen, and University Medical Center Utrecht
Full project title: Protective human antibodies against multidrug resistant Staphylococcus aureus
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Developing a remedy against a life-threatening bacterium